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What would you do if had an incurable disease and heard that something simple and common may help -- a chemical found at a pet store, or in an allergy drug, or a breakthrough injection a man in California developed? It's the sort of dilemma Alan Romantowski, a former airline pilot, faces with each news story about Alzheimer's disease treatments. "It is tempting; I'm taking ginseng, fish oil, ginkgo and all the over-the-counter things that the doctors say don't have any proof that it helps, but it doesn't hurt," said Romantowski, 55, who is suffering from the early stages of the disease. Whether scientifically sound or wacky, any news about potential Alzheimer's treatments can fill a doctor's voicemail with calls from desperate families. And a new potential treatment announced Tuesday may be no exception. Discussed at the annual Alzheimer's Association Meeting in Chicago, a drug called Rember sparked hope among researchers and within the Alzheimer community. Rember has completed a phase II trial, which means it's a long way off from meeting FDA approval as a legal therapy. But, thus far the data has shown promise -- double the improvement in cognition than a placebo gives for patients with moderate Alzheimer's disease. "There was an article about that in our paper this morning," said Josie Romantowski. "I actually even called my husband about it... as far as trying [a drug], what is there to lose really, at this point?"
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The Dark Side, Jane Mayer’s gripping new account of the war on terror, is really the story of two wars: the far-flung battle against Islamic radicalism, and the bitter, closed-doors domestic struggle over whether the president should have limitless power to wage it. The war on terror, according to Ms. Mayer, ... was a "political battle cloaked in legal strategy, an ideological trench war" waged by a small group of true believers whose expansive views of executive power she traces from the Nixon administration through the Iran-contra scandal to the panicked days after 9/11. Ms. Mayer’s prime movers and main villains are Vice President Dick Cheney and his legal counsel (now chief of staff) David Addington, who after the terrorist attacks moved to establish "a policy of deliberate cruelty that would’ve been unthinkable on Sept. 10." As the leader of the self-styled "war council," a group of lawyers who took the lead in making the rules for the war on terror, Mr. Addington startled many colleagues with the depth of his fervor and the reach of his power. The war council settled on a "pre-emptive criminal model," in which suspects would be used — more or less indefinitely — to gather evidence of future crimes rather than held accountable for previous ones. There would be minimal oversight from Congress. The C.I.A. would take the lead, developing aggressive new interrogation methods that would be described as “enhanced,” “robust,” “special.” What they were not, a series of secret memos issued by John Yoo and others at the Office of Legal Council would attempt to certify, was “torture.”
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The former Colombian hostage Ingrid Betancourt returned to what she called her "other family" in France today as doubt was cast on the apparently daring rescue that won her freedom. While she was still in the air, the Swiss radio station RSR broadcast a report questioning the official version of the operation to free Ms Betancourt and 14 other hostages -- saying that money, not cunning, had clinched their freedom. RSR said that the 15 hostages "were in reality ransomed for a high price, and the whole operation afterwards was a set-up". Citing a source "close to the events, reliable and tested many times in recent years", it said that the United States -- which had three citizens among those freed -- was behind the deal and put the price at $20 million. The Colombian Foreign Ministry furiously denied the allegations, with a spokesman calling them "completely false." He added: "They are lies". General Freddy Padilla, head of the Colombian military, categorically denied they had paid "a single peso" to Farc. The French Foreign Ministry denied any involvement in any deal. The US has not responded to the [allegations].
While carrying out field work in Papua New Guinea in the late 1980s, [Dr. David Pritchard] noticed that Papuans infected with the Necator americanus hookworm, a parasite that lives in the human gut, did not suffer much from an assortment of autoimmune-related illnesses, including hay fever and asthma. Over the years, Dr. Pritchard has developed a theory to explain the phenomenon. "The allergic response evolved to help expel parasites, and we think the worms have found a way of switching off the immune system in order to survive," he said. "That's why infected people have fewer allergic symptoms." To test his theory, and to see whether he can translate it into therapeutic pay dirt, Dr. Pritchard is recruiting clinical trial participants willing to be infected with 10 hookworms each in hopes of banishing their allergies and asthma. Never one to sidestep his own experimental cures, Dr. Pritchard initially used himself as a subject. After Dr. Pritchard's self-infection experiment, the National Health Services ethics committee let him conduct a study in 2006 with 30 participants, 15 of whom received 10 hookworms each. Tests showed that after six weeks, the T-cells of the 15 worm recipients began to produce lower levels of chemicals associated with inflammatory response, indicating that their immune systems were more suppressed than those of the 15 placebo recipients. Despite playing host to small numbers of parasites, worm recipients reported little discomfort. Trial participants raved about their allergy symptoms disappearing.
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Peace campaigners have welcomed reports that the US military has withdrawn its last nuclear weapons from Britain. The Federation of American Scientists said in a report 110 nuclear bombs were removed from RAF Lakenheath in Suffolk. The US military said it was policy not to confirm or deny the presence of nuclear weapons at Lakenheath. Kate Hudson, from the Campaign for Nuclear Disarmament (CND), said: "We would like official confirmation from the government that this has happened." She added: "We believe an open admission will be a confidence-boosting measure for future disarmament initiatives." The report's author, Hans Kristensen, said the move had happened in the past few years. Mr Kristensen, an expert on the US nuclear arsenal, said the withdrawal of the bombs [is] part of a general strategic shift since the end of the Cold War. The Suffolk base has been the site of many protests over the years, mainly due to the claims that nuclear bombs were stored at the base.
Gov. Matt Blunt signed a bill ... prohibiting companies in Missouri from forcing workers to have microchips implanted in their bodies. You read that right. In Missouri, it’s now illegal for businesses to require employees to have a microchip embedded under their skin. “When you’re forced to have a chip put in you as a condition of employment, that’s taking away your civil liberties and your freedom,” said Rep. Jim Guest, a King City Republican. Guest added the microchip language to a bill concerning overtime and disability benefits. Next year, he said, he will introduce a bill to prohibit all microchip implants in humans. Only a few hundred people nationwide have been voluntarily implanted with the devices, and mandated microchips are virtually unheard of in Missouri or anywhere else. But three other states already prohibit mandatory implants. Guest ... said it’s crucial to ban the technology before it gains any traction. “We want a law on the books so we can stop a major problem before it starts,” he said. Privacy advocates and others worry that widespread use of such chips could allow individuals to be tracked or monitored without their knowledge and create identity theft issues. The chips, which use radio frequency identification [RFID] technology, are about the size of a grain of rice and are usually implanted in the upper arm. Guest and others have raised health concerns as well, citing studies that link implanted chips with cancerous tumors in laboratory animals.
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Smokers trying to quit sometimes use nicotine patches to fight their tobacco dependence. But patches don't work for everyone. New research suggests that patches might be made more effective if used in combination with hypnosis, just as they tend to work better when used in conjunction with professional counseling. A recently published study showed hypnotherapy to be as effective as standard behavioral counseling when combined with nicotine patches in helping smokers to quit and stay off cigarettes for one year. "This study provides much-needed evidence that hypnosis is indeed a very helpful treatment," says lead author Timothy Carmody. During hypnotherapy, Carmody explained, patients are coaxed into a relaxed state and then provided with a series of skills for coping with withdrawal symptoms and the urge to smoke. A total of 286 participants were randomly divided and received either hypnosis or standard behavioral counseling aimed at smoking cessation. Hypnosis was particularly helpful for would-be quitters who reported a history of depression. That finding suggests that smokers who have struggled with depression—or perhaps with other psychiatric conditions, Carmody says—might someday receive hypnosis as part of the quitting process. Brian Hitsman, assistant professor of preventive medicine at Northwestern University's Feinberg School of Medicine, called the results encouraging and added that the hypnotic intervention evaluated in the study may have the potential to serve as another nonpharmacological treatment option in addition to standard counseling.
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Four Western oil companies are in the final stages of negotiations this month on contracts that will return them to Iraq, 36 years after losing their oil concessions to nationalization as Saddam Hussein rose to power. Exxon Mobil, Shell, Total and BP — the original partners in the Iraq Petroleum Company — along with Chevron and a number of smaller oil companies, are in talks with Iraq’s Oil Ministry for no-bid contracts to service Iraq’s largest fields. The deals, expected to be announced on June 30, will lay the foundation for the first commercial work for the major companies in Iraq since the American invasion, and open a new and potentially lucrative country for their operations. The no-bid contracts are unusual for the industry, and the offers prevailed over others by more than 40 companies, including companies in Russia, China and India. The contracts [would] give the companies an advantage in bidding on future contracts. There was suspicion among many in the Arab world and among parts of the American public that the United States had gone to war in Iraq precisely to secure the oil wealth these contracts seek to extract. The Bush administration has said that the war was necessary to combat terrorism. Sensitive to the appearance that they were profiting from the war and already under pressure because of record high oil prices, senior officials of two of the companies, speaking only on the condition that they not be identified, said they were helping Iraq rebuild its decrepit oil industry.
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A man who had been given less than a year to live had a complete remission of advanced deadly skin cancer after an experimental treatment that revved up his immune system to fight the tumors. The 52-year-old patient's dramatic turnaround was the only success in a small study, leading doctors to be cautious in their enthusiasm. However, the treatment reported in ... The New England Journal of Medicine is being counted as the latest in a small series of successes involving immune-priming treatments against deadly skin cancers. "Immunotherapy has become the most promising approach" to late-stage, death-sentence skin cancers, said Dr. Darrell Rigel, a dermatology researcher at the New York University Cancer Institute in New York. About 20 years ago, some scientists discovered that immune cells could latch onto and attack skin cancers. "There's a long history behind all of this," said Dr. Steven Rosenberg of the National Cancer Institute. In recent experiments, Rosenberg and other researchers have focused on souping up a certain kind of immune system cell - the "killer T cells" that envelop and kill foreign agents. Scientists focused ... on specific helper T cells that are adept at locking onto a cancer cell and guiding the killer cells to their target. The researchers drew blood from patients, located the special helper cells and then grew more of them in the laboratory. They then infused roughly 5 billion of the cells back into the patients without chemotherapy or the other harsh drugs. "It's a simpler and less toxic approach to melanoma than had been previously employed," said Dr. Louis Weiner, director of the cancer center at Georgetown University.
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Shai Agassi, a Silicon Valley entrepreneur, pledges that he can beat the spiraling cost of gasoline with the world's first mass-produced electric car. In January, Israel's government endorsed the Palo Alto businessman's ambitious joint venture between his startup company - Project Better Place - and Renault-Nissan. Agassi says he raised $200 million to get the $500 million dollar project, which will include a network of charging and battery-exchange stations by 2010, off the ground. Project Better Place also has signed an agreement with Denmark to begin a similar operation by 2011. In Denmark, a pioneer in developing wind power, batteries are expected to be recharged using wind-powered turbines. Agassi is banking on his electric-powered sedan revolutionizing life on the roads, cleaning up the environment and reducing dependence on oil. The cars are expected to have a range of up to 140 miles per charge and a top speed of 68 mph - the speed limit in Israel. Last month, he invited reporters to test-drive a prototype that looks a lot like the Renault Megane, a four-door sedan. The car is noticeably quiet and has no exhaust pipe, an electric socket in place of a gas cap and a dashboard gauge that measures the charge of the vehicle's 450-pound lithium-ion battery. In the United States, Hawaii Gov. Linda Lingle has said she is interested in her state becoming the first to embrace the electric-car network. Mayor Gavin Newsom also has reportedly expressed interest in making San Francisco the first U.S. metropolis to place electric cars on city roads.
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New IRS statistics show 7,389 federal tax returns with $200,000 or more in adjusted gross income reported no federal income taxes in 2005. That's a 161% jump from the 2,833 comparable returns filed in 2004. Additionally, 4,224 of the over-$200,000 earners reported no worldwide income tax liability on their 2005 returns. That represents a 75% increase from the 2,420 comparable returns filed in 2004. The data ... show a rising number of high-income earners have avoided the alternative minimum tax, which was intended to ensure that tax shelters, deductions and loopholes wouldn't exempt wealthy Americans from paying at least some federal income tax. The increases stem in part from two tax law changes. Responding to Hurricane Katrina, Washington exempted charitable contributions between Aug. 27, 2005, and Jan. 1, 2006, from the overall limit on itemized tax deductions and the 50% of adjusted gross income limit for such giving. [But] the one-time change wasn't limited to hurricane-related contributions. [And] under the American Jobs Creation Act of 2004, Washington also allowed taxpayers to eliminate up to 100% of their alternative minimum tax liability by using credits for any foreign taxes paid. In 2004, IRS data show [high-income earners] reported $16.6 million in foreign tax credits. The following year, the total credits claimed soared to $447.3 million. "My sense of it is that the people who introduce these provisions know exactly who is going to benefit," [said Howard Gleckman, a senior research associate and tax blog editor at The Tax Policy Center].
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Attorney General Michael B. Mukasey rejected ... the idea of creating a national task force to combat the country’s mortgage fraud crisis, calling the problem a localized one akin to “white-collar street crimes.” He gave his most definitive answer ... in a briefing for reporters, saying that he did not think that the kind of national task force created at the Justice Department in 2002 to investigate the collapse of Enron was “the proper response” to the current crisis. Some critics have called for the same sort of broad federal law enforcement response seen in the Enron case and a wave of other corporate scandals earlier this decade, or in the collapse of the savings and loan industry in the 1980s and 1990s. “This is disappointing,” Representative Barney Frank, the Massachusetts Democrat who leads the House financial services committee, said. Calling the mortgage crisis “worse than Enron,” Mr. Frank said “Enron didn’t cause a worldwide recession. This has more innocent victims.” Mr. Frank noted that a $2.4 billion bill to prevent mortgage foreclosure, which has already passed the House, includes a provision backed by Republicans to provide an additional $300 million for law enforcement officials to fight mortgage fraud. He questioned how that money could be spent without a more centralized effort. The Federal Bureau of Investigation is investigating 19 major corporate fraud cases related to the mortgage crisis. The targets of most of those investigations have not been disclosed. In addition, the F.B.I. has 1,380 small mortgage fraud investigations now open in field offices around the country.
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When Khalid Shaikh Mohammed and his alleged collaborators in the Sept. 11 terrorist attacks appear before the war crimes tribunal here today, ousted chief prosecutor Col. Morris D. Davis will not be celebrating. Davis, who has spent half of his life in the military justice system, still considers it "the most ethical process in the world." But the Pentagon's push to prosecute the so-called 9/11 Five is tainted, in his view, by political intrusions, illegal influence applied by more-senior officers and reliance on evidence obtained through coercion or torture. Davis drew the wrath of many in the Pentagon hierarchy when he objected last fall to pressures from Bush administration political appointees to prosecute Mohammed, known in intelligence circles as KSM, ahead of other war crimes suspects whose cases were already researched and on whom vital evidence was declassified. Unless the evidence prosecutors have against Mohammed and his codefendants is declassified, much of their prosecution will be conducted behind closed doors, depriving the American media and public of a clear view of the proceedings, he says. Davis ran afoul of superiors ... when he advised his prosecutors against relying on evidence obtained through waterboarding and other interrogation techniques that have been deemed coercive or tantamount to torture. Davis resigned after political appointees at the Pentagon rejected his judgment on the choice of cases to be tried in the months leading up to this November's election, as well as his advice against building prosecutions on coerced and potentially unreliable confessions.
Is 90 the new 50? Not yet, aging researchers say, but medical breakthroughs to significantly extend life and ease the ailments of getting older are closer than many people think. "The general public has no idea what's coming," said David Sinclair, a Harvard Medical School professor who has made headlines with research into the health benefits of a substance found in red wine called resveratrol. He said scientists can greatly increase longevity and improve health in lab animals like mice, and that drugs to benefit people are on the way. "It's not an if, but a when." Sinclair said treatments could be a few years or a decade away, but they're "really close. It's not something (from) science fiction and it's not something for the next generation." Robert Butler, a pioneer of aging research who won the Pulitzer Prize in 1976 for the book Why Survive? Being Old in America, [said] that "people live longer and better by having a sense of purpose." He said that while medicine and biology are important for longevity, having friendships and close relationships also have a big impact. Richard Weindruch, a professor at the University of Wisconsin ... studies how extremely low-calorie diets affect aging. Sinclair said that based on Weindruch's work, he set out a decade ago to find the genes involved in caloric restriction and find a pill that can provide the benefits "without you feeling hungry all the time." He described how his research found that mice given large doses of resveratrol "live longer, they're almost immune to the effects of obesity. They don't get diabetes, cancer, Alzheimer's as frequently. We delay the diseases of aging."
With a population nearing 3 million, Guayaquil [Ecuador] is home to more than 200 gangs and 60,000 gang youth. But in recent months, this neighbourhood has become a Barrio de Paz (“peace town”) under the guidance of Ser Paz, an organization committed to fostering peace in Guayaquil’s violent neighbourhoods. Support comes from Nelsa Curbelo, a 66-year-old woman who looks more like a friendly grandmother passing time with neighbourhood children than a pioneer of social reform working in the most dangerous city in Ecuador. Curbelo has been playing against type for years. When she founded Ser Paz (“being peace”) in 1999, she began her work by not working at all. Instead of establishing programs, she spent almost two years listening to the young people she’d later serve: walking the neighbourhoods of Guayaquil alone, sometimes after dark, talking with those who’d talk to her, learning about gangs and impressing the youth with her fearless willingness to be present on their streets. It’s these qualities of presence and acceptance that distinguish Curbelo from others who work with gangs. Instead of dismissing gang culture, she validates the positive elements it inspires: teamwork, commitment, a sense of belonging and quick communication. She refuses to label gang members “delinquents,” and suggests the instinct to come together in “teams” is a positive response by area youth to “a very unfair and unequal society.”
Amid increasing public outcry over record-shattering oil and gas prices, senators ... hauled industry executives in to testify about the recent runup. The Senate Judiciary Committee ... grilled executives from Exxon Mobil, ConocoPhillips Co., Shell Oil Co., Chevron and BP as to how their companies can in good conscience make so much money, while American drivers pay so much at the pump. Sen. Richard Durbin, D-Ill. [asked] "Does it trouble any one of you - the costs you're imposing on families, on small businesses, on truckers?" The hearing marked the second time in as many months that top oil industry officials have been called before Congress. The hearing was ostensibly called to ask the executives why they needed some $18 billion in federal subsidies in light of their record profits, but quickly became a Q&A on bigger questions in the energy business. Lawmakers criticized the firms for not investing enough in finding new oil and developing renewable resources and told them, in thinly disguised terms, that they'd be forced to enact extra profit taxes if Big Oil continued to post such large earnings. Although lawmakers don't vote on energy issues strictly along party lines, Democrats generally want to increase taxes on Big Oil and use the money to fund renewable energy research. Republicans generally favor opening up the Alaska Wildlife Refuge, large parts of the Rocky Mountains, and areas off the east and west coast that have been closed to drilling since the 1970s following a public backlash after several big oil spills.
More than 360 workers who dealt with the aftermath of the World Trade Center disaster have died, state health officials said Wednesday. Officials have determined the cause of death of 154 of the responders and volunteers who toiled at Ground Zero, the blocks nearby and at the Fresh Kills landfill, where debris from the site was taken. Of those, 80 died of cancer. "It's the tip of the iceberg," said David Worby, who is representing 10,000 workers - 600 with cancer - who say they got sick after working on rescue and recovery efforts. "These statistics bear out how toxic that site was," Worby said. Most of the deadly tumors were in the lungs and digestive system, according to the tally from the state's World Trade Center Responder Fatality Investigation Program. Other deaths were traced to blood cancers and heart and circulatory diseases. Five ex-workers committed suicide, said Kitty Gelberg, who is tracking the deaths for the program. Gelberg said ... there is an overall undercount of workers who have died. Last year, the head of Mount Sinai Medical Center's monitoring and treatment program, Dr. Robin Herbert, predicted a "third wave" of 9/11-related deaths from cancer. Cathy Murray, whose husband, Fire Lt. John Murray, died of colon cancer April 30, "absolutely" connects his disease to his work at Ground Zero. He was diagnosed in June and was 52 when he died, she said. "He was perfectly healthy," said Cathy Murray, 53, of Staten Island. "He never smoked a day in his life, and neither did I. It happened so quick and so aggressive. He was responding at first, but then he wasn't," she added. "And now he's gone."
Note: For a powerful summary of reports from major media sources questioning the official story of what happened on 9/11, click here.
An audit of US-funded reconstruction projects for Iraq has found millions of dollars have been wasted because many schemes have never been completed. The Special Inspector General for Iraq Reconstruction blamed delays, costs, poor performance and violence for failure to finish some 855 projects. Many other projects had been falsely described as complete, found the audit of 47,321 reconstruction projects. Iraq reconstruction has cost US taxpayers more than $100bn so far. USAID, the body responsible for overseeing Iraqi reconstruction, has responded that the database used for the review was incomplete. The audit by Senator Stuart Bowen found US officials had terminated at least 855 projects before completion. Of this number, 112 were ended because of the contractors' poor performance. Danielle Brian, executive director of the watchdog group Project on Government Oversight, said: "The report paints a depressing picture of money being poured into failed Iraq reconstruction projects. Contractors are killed, projects are blown up just before being completed, or the contractor just stops doing the work." Last year, congressional investigators said as much as $10bn (Ł5bn) charged by US contractors for Iraq reconstruction had been questionable.
Note: Why is the U.S. spending over $100 billion to "reconstruct" Iraq? That's over $500 for each taxpayer in the U.S., with little to show for it. For more, see what a highly decorated U.S. general has to say on all this by clicking here.
A remote drilling rig high in the Mackenzie Delta has become the site of a breakthrough that could one day revolutionize the world's energy supply. For the first time, Canadian and Japanese researchers have managed to efficiently produce a constant stream of natural gas from ice-like gas hydrates that, worldwide, dwarf all known fossil fuel deposits combined. "We were able to sustain flow," said Scott Dallimore, the Geological Survey of Canada researcher in charge of the remote Mallik drilling program. "It worked." For a decade now, Dallimore and scientists from a half-dozen other countries have been returning to a site on Richards Island on the very northwestern tip of the Northwest Territories to study methane gas hydrates. A hydrate is created when a molecule of gas – in this case, methane or natural gas – is trapped by high pressures and low temperatures inside a cage of water molecules. The result is almost – but not quite – ice. It's more like a dry, white slush suffusing the sand and gravel 1,000 metres beneath the Mallik rig. Heat or unsqueeze the hydrate and gas is released. Hold a core sample to your ear and it hisses. More significant is the fact that gas hydrates concentrate 164 times the energy of the same amount of natural gas. And gas hydrate fields are found in abundance under the coastal waters of every continent. Calculations suggest there's more energy in gas hydrates than in coal, oil and conventional gas combined. Last month, the Mallik team became the first to use that method to get a steady, consistent flow. "That went really well," said Dallimore. "We definitely demonstrated that these hydrates are responsive enough that you can sustain flow. We were able to take conventional technologies, modify them, and produce. That's a big step forward."
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Money can buy happiness, but only if you spend it on someone else. Spending as little as $5 a day on someone else could significantly boost happiness, [a] team at the University of British Columbia and Harvard Business School found. Their experiments on more than 630 Americans showed they were measurably happier when they spent money on others -- even if they thought spending the money on themselves would make them happier. "We wanted to test our theory that how people spend their money is at least as important as how much money they earn," said Elizabeth Dunn, a psychologist at the University of British Columbia. They asked their 600 volunteers first to rate their general happiness, report their annual income and detail their monthly spending including bills, gifts for themselves, gifts for others and donations to charity. "Regardless of how much income each person made, those who spent money on others reported greater happiness, while those who spent more on themselves did not," Dunn said. Dunn's team also surveyed 16 employees at a company in Boston before and after they received an annual profit-sharing bonus of between $3,000 and $8,000. "Employees who devoted more of their bonus to pro-social spending experienced greater happiness after receiving the bonus, and the manner in which they spent that bonus was a more important predictor of their happiness than the size of the bonus itself," they wrote in their report, published in the journal Science. "Finally, participants who were randomly assigned to spend money on others experienced greater happiness than those assigned to spend money on themselves," they said. "These findings suggest that very minor alterations in spending allocations -- as little as $5 -- may be enough to produce real gains in happiness on a given day."
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